Smart reconstitution optimizer reference
How the optimizer works
Reconstitution is a single relationship between four numbers: the vial mass, the
dose, the BAC water you add, and the resulting draw on a U-100 syringe. Fix the
vial and dose, and the draw is decided entirely by how much water you add. The
optimizer walks a set of clean target draws and inverts the relationship to find
the BAC water that lands exactly on each one:
BAC water mL = (draw units × vial mg) ÷ (dose mg × 100)
The ÷100 comes from the U-100 syringe, where 1 unit = 0.01 mL.
Worked example: a 10 mg vial dosed at 2.5 mg, aiming for a 50-unit draw, needs
(50 × 10) ÷ (2.5 × 100) = 2 mL of BAC water, which
is also the cleanest, easiest mark to read.
Why a round draw matters
Insulin syringes are marked in whole units, and the gaps between marks are small.
A draw that lands on 50 units is unambiguous; a draw of 47 or 53 units invites a
misread, especially in poor light or with tired eyes. Choosing the BAC water so
the dose falls on a round number removes that guesswork at every injection, which
matters most when the same protocol is repeated many times.
Easier to read vs smaller volume
Easier to read favors larger, well-spaced draws that sit near the
middle of the syringe and land on a 10- or 5-unit mark, even if that means
injecting slightly more fluid. Smaller volume favors the least
fluid per injection while still keeping the draw reasonably round. The optimizer
also flags a round water amount when a recipe uses a tidy BAC
volume like 1.0, 1.5, or 2.0 mL, which is simpler to measure into the vial.
Units & conversions
Doses are entered in micrograms or milligrams, where 1 mg = 1000 mcg.
Syringe volume relates to draw as 1 mL = 100 units, so 0.01 mL = 1 unit. Vial
concentration after reconstitution is the vial mass divided by the BAC water added,
shown in mg/mL on each recipe.
BAC water on hand
If you only have a small bottle of bacteriostatic water, enter the amount you can
spare and the optimizer restricts its recommendations to recipes that fit within
it. Left blank, it considers practical bottle volumes up to 5 mL.
Data handling and privacy
The optimizer computes entirely in your browser. Nothing you enter is transmitted
or stored; a share link simply encodes your inputs in the page address so the same
result reopens.
Scope & safety
PepRecon is a research and education resource. This optimizer and reference
material are provided for informational purposes and are not medical advice; they
do not establish a dosing recommendation. Consult a qualified clinician before use.
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